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Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: insights from the reduction of atherothrombosis for continued health (REACH) registry.

Publication ,  Journal Article
Meadows, TA; Bhatt, DL; Hirsch, AT; Creager, MA; Califf, RM; Ohman, EM; Cannon, CP; Eagle, KA; Alberts, MJ; Goto, S; Smith, SC; Wilson, PWF ...
Published in: Am Heart J
December 2009

BACKGROUND: Prior investigations to define ethnic-related differences in the risks, medical treatment, and outcomes of patients with peripheral arterial disease (PAD) have been limited. METHODS: The impact of ethnicity on the risk factor profiles, use of evidence-based medical therapies, and 2-year cardiovascular outcomes were investigated in 2,168 individuals (blacks n = 237, Hispanics n = 115, whites n = 1,816) from the United States with PAD from the international Reduction of Atherothrombosis for Continued Health Registry. RESULTS: Blacks and Hispanics were more likely to have diabetes mellitus and hypertension, whereas whites had a higher rate of diagnosed hypercholesterolemia. Control of blood pressure and cholesterol levels differed significantly in the groups at baseline: elevated blood pressure was present in 55% of blacks versus 48% of Hispanics versus 38% of whites (P < .01), whereas 41% of blacks versus 31% of Hispanics versus 25% of whites had elevated total cholesterol (P < .01). Aspirin use (62% of blacks vs 68% of Hispanics vs 72% of whites, P < .01) and statin use (72% of blacks vs 68% of Hispanics vs 77% of whites, P = .03) also varied significantly. In this context, rates by ethnicity for cardiovascular death, myocardial infarction, or stroke seemed to be no different at 2 years, at 8.8% for the total population: 11.6% for blacks, 8.5% for whites, and 5.0% for Hispanics (P = .32). Fewer blacks (0.6%) had undergone peripheral arterial bypass surgery compared with whites (3.4%) and Hispanics (5.2%) (P = .02). CONCLUSIONS: Ethnic-related differences have been documented in the prevalence and treatment of several atherosclerotic risk factors known to be associated with PAD, including a variation in the use of surgical revascularization procedures.

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Published In

Am Heart J

DOI

EISSN

1097-6744

Publication Date

December 2009

Volume

158

Issue

6

Start / End Page

1038 / 1045

Location

United States

Related Subject Headings

  • White People
  • United States
  • Risk Factors
  • Registries
  • Prevalence
  • Peripheral Vascular Diseases
  • Outpatients
  • Male
  • Humans
  • Hispanic or Latino
 

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Meadows, T. A., Bhatt, D. L., Hirsch, A. T., Creager, M. A., Califf, R. M., Ohman, E. M., … REACH Registry Investigators, . (2009). Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: insights from the reduction of atherothrombosis for continued health (REACH) registry. Am Heart J, 158(6), 1038–1045. https://doi.org/10.1016/j.ahj.2009.09.014
Meadows, Telly A., Deepak L. Bhatt, Alan T. Hirsch, Mark A. Creager, Robert M. Califf, E Magnus Ohman, Christopher P. Cannon, et al. “Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: insights from the reduction of atherothrombosis for continued health (REACH) registry.Am Heart J 158, no. 6 (December 2009): 1038–45. https://doi.org/10.1016/j.ahj.2009.09.014.
Meadows TA, Bhatt DL, Hirsch AT, Creager MA, Califf RM, Ohman EM, Cannon CP, Eagle KA, Alberts MJ, Goto S, Smith SC, Wilson PWF, Watson KE, Steg PG, REACH Registry Investigators. Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: insights from the reduction of atherothrombosis for continued health (REACH) registry. Am Heart J. 2009 Dec;158(6):1038–1045.
Journal cover image

Published In

Am Heart J

DOI

EISSN

1097-6744

Publication Date

December 2009

Volume

158

Issue

6

Start / End Page

1038 / 1045

Location

United States

Related Subject Headings

  • White People
  • United States
  • Risk Factors
  • Registries
  • Prevalence
  • Peripheral Vascular Diseases
  • Outpatients
  • Male
  • Humans
  • Hispanic or Latino