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Assessing the Value of Newer Pharmacologic Agents in Non-ST Elevation Patients: A Decision Support System Application

Publication ,  Journal Article
Eisenstein, EL; Peterson, ED; Jollis, JG; Tardiff, BE; Califf, RM; Knight, JD; Mark, DB
Published in: Journal of the American Medical Informatics Association
January 1, 1997

Newer pharmacologic agents have demonstrated significant clinical and economic benefit in high-risk percutaneous transluminal coronary angioplasty (PTCA) patients. However, the higher costs of these agents may prohibit their use in lower-risk coronary artery disease (CAD) populations. We developed a decision support system (DSS) to determine the level of clinical effectiveness these newer agents must exhibit to be either cost-neutral or cost-effective in non-ST elevation patients. Our DSS evaluated six month cumulative costs, increased years of life saved (YOLS), and lifetime cost-effectiveness. We found that these therapies can cost as much as $1500 and be cost-neutral at six months if they reduce the composite endpoint of death, myocardial infarction (MI), or revascularization by 15%, and they may cost as much as $3000 and be cost-effective if they reduce this endpoint by 10%.

Duke Scholars

Published In

Journal of the American Medical Informatics Association

ISSN

1067-5027

Publication Date

January 1, 1997

Volume

4

Issue

SUPPL.

Start / End Page

273 / 277

Related Subject Headings

  • Medical Informatics
  • 46 Information and computing sciences
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences
  • 09 Engineering
  • 08 Information and Computing Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Eisenstein, E. L., Peterson, E. D., Jollis, J. G., Tardiff, B. E., Califf, R. M., Knight, J. D., & Mark, D. B. (1997). Assessing the Value of Newer Pharmacologic Agents in Non-ST Elevation Patients: A Decision Support System Application. Journal of the American Medical Informatics Association, 4(SUPPL.), 273–277.
Eisenstein, E. L., E. D. Peterson, J. G. Jollis, B. E. Tardiff, R. M. Califf, J. D. Knight, and D. B. Mark. “Assessing the Value of Newer Pharmacologic Agents in Non-ST Elevation Patients: A Decision Support System Application.” Journal of the American Medical Informatics Association 4, no. SUPPL. (January 1, 1997): 273–77.
Eisenstein EL, Peterson ED, Jollis JG, Tardiff BE, Califf RM, Knight JD, et al. Assessing the Value of Newer Pharmacologic Agents in Non-ST Elevation Patients: A Decision Support System Application. Journal of the American Medical Informatics Association. 1997 Jan 1;4(SUPPL.):273–7.
Eisenstein, E. L., et al. “Assessing the Value of Newer Pharmacologic Agents in Non-ST Elevation Patients: A Decision Support System Application.” Journal of the American Medical Informatics Association, vol. 4, no. SUPPL., Jan. 1997, pp. 273–77.
Eisenstein EL, Peterson ED, Jollis JG, Tardiff BE, Califf RM, Knight JD, Mark DB. Assessing the Value of Newer Pharmacologic Agents in Non-ST Elevation Patients: A Decision Support System Application. Journal of the American Medical Informatics Association. 1997 Jan 1;4(SUPPL.):273–277.
Journal cover image

Published In

Journal of the American Medical Informatics Association

ISSN

1067-5027

Publication Date

January 1, 1997

Volume

4

Issue

SUPPL.

Start / End Page

273 / 277

Related Subject Headings

  • Medical Informatics
  • 46 Information and computing sciences
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences
  • 09 Engineering
  • 08 Information and Computing Sciences