Nutritional control via Tor signaling in Saccharomyces cerevisiae.
Journal Article (Journal Article;Review)
The yeast Saccharomyces cerevisiae senses and responds to nutrients by adapting its growth rate and undergoing morphogenic transitions to ensure survival. The Tor pathway is a major integrator of nutrient-derived signals that in coordination with other signaling pathways orchestrates cell growth. Recent advances have identified novel Tor kinase substrates and established the protein trafficking membranous network and the nucleus as platforms for Tor signaling. These and other recent findings delineate distinct signaling branches emanating from membrane-associated Tor complexes to control cell growth.
Full Text
Duke Authors
Cited Authors
- Rohde, JR; Bastidas, R; Puria, R; Cardenas, ME
Published Date
- April 2008
Published In
Volume / Issue
- 11 / 2
Start / End Page
- 153 - 160
PubMed ID
- 18396450
Pubmed Central ID
- PMC2394285
International Standard Serial Number (ISSN)
- 1369-5274
Digital Object Identifier (DOI)
- 10.1016/j.mib.2008.02.013
Language
- eng
Conference Location
- England