Nutritional control via Tor signaling in Saccharomyces cerevisiae.

Journal Article (Journal Article;Review)

The yeast Saccharomyces cerevisiae senses and responds to nutrients by adapting its growth rate and undergoing morphogenic transitions to ensure survival. The Tor pathway is a major integrator of nutrient-derived signals that in coordination with other signaling pathways orchestrates cell growth. Recent advances have identified novel Tor kinase substrates and established the protein trafficking membranous network and the nucleus as platforms for Tor signaling. These and other recent findings delineate distinct signaling branches emanating from membrane-associated Tor complexes to control cell growth.

Full Text

Duke Authors

Cited Authors

  • Rohde, JR; Bastidas, R; Puria, R; Cardenas, ME

Published Date

  • April 2008

Published In

Volume / Issue

  • 11 / 2

Start / End Page

  • 153 - 160

PubMed ID

  • 18396450

Pubmed Central ID

  • PMC2394285

International Standard Serial Number (ISSN)

  • 1369-5274

Digital Object Identifier (DOI)

  • 10.1016/j.mib.2008.02.013

Language

  • eng

Conference Location

  • England