Food for thought: the physiological relevance of ghrelin and dopamine D2 receptor heterodimerization in the regulation of appetite.

Journal Article

Establishing whether G protein-coupled receptors (GPCRs) form physiologically relevant functional homo- and heteroligomers in vivo has been a major biochemical challenge. In this issue of Neuron, Kern et al. (2012) investigate whether the anorexigenic effects of D2 dopamine receptors may be a direct consequence of allosteric modulation by Apo-ghrelin receptors.

Full Text

Duke Authors

Cited Authors

  • Salahpour, A; Caron, MG

Published Date

  • January 2012

Published In

Volume / Issue

  • 73 / 2

Start / End Page

  • 210 - 211

PubMed ID

  • 22284175

Pubmed Central ID

  • 22284175

Electronic International Standard Serial Number (EISSN)

  • 1097-4199

International Standard Serial Number (ISSN)

  • 0896-6273

Digital Object Identifier (DOI)

  • 10.1016/j.neuron.2012.01.004


  • eng