Are there effective new strategies for the treatment of acute and chronic GvHD?


Journal Article (Review)

The molecular biology and pathophysiology underlying graft-versus-host disease (GvHD) remains an area of intensive research. Understanding normal and abnormal developments of both the innate and adaptive immune systems are beginning to provide understanding of the details of relevant pathways. Recent work in gene-expression profiling suggests a critical next step in identifying broader patterns that will stand up to examination in independent data sets and provide a sturdy basis for targeted therapy and preventive measures against GvHD.

Full Text

Duke Authors

Cited Authors

  • Chao, NJ

Published Date

  • March 2008

Published In

Volume / Issue

  • 21 / 1

Start / End Page

  • 93 - 98

PubMed ID

  • 18342817

Pubmed Central ID

  • 18342817

International Standard Serial Number (ISSN)

  • 1521-6926

Digital Object Identifier (DOI)

  • 10.1016/j.beha.2007.11.012


  • eng

Conference Location

  • Netherlands