Glucose challenge test screening for prediabetes and undiagnosed diabetes.

Journal Article (Journal Article)

AIMS/HYPOTHESIS: Diabetes prevention and care are limited by lack of screening. We hypothesised that screening could be done with a strategy similar to that used near-universally for gestational diabetes, i.e. a 50 g oral glucose challenge test (GCT) performed at any time of day, regardless of meal status, with one 1 h sample. METHODS: At a first visit, participants had random plasma and capillary glucose measured, followed by the GCT with plasma and capillary glucose (GCTplasma and GCTcap, respectively). At a second visit, participants had HbA(1c) measured and a diagnostic 75 g OGTT. RESULTS: The 1,573 participants had mean age of 48 years, BMI 30.3 kg/m(2) and 58% were women and 58% were black. Diabetes (defined by WHO) was present in 4.6% and prediabetes (defined as impaired glucose tolerance [2 h glucose 7.8-11.1 (140-199 mg/dl) with fasting glucose

Full Text

Duke Authors

Cited Authors

  • Phillips, LS; Ziemer, DC; Kolm, P; Weintraub, WS; Vaccarino, V; Rhee, MK; Chatterjee, R; Narayan, KMV; Koch, DD

Published Date

  • September 2009

Published In

Volume / Issue

  • 52 / 9

Start / End Page

  • 1798 - 1807

PubMed ID

  • 19557386

Electronic International Standard Serial Number (EISSN)

  • 1432-0428

Digital Object Identifier (DOI)

  • 10.1007/s00125-009-1407-7


  • eng

Conference Location

  • Germany