African strains of hepatitis E virus that are distinct from Asian strains.
Publication
, Journal Article
Chatterjee, R; Tsarev, S; Pillot, J; Coursaget, P; Emerson, SU; Purcell, RH
Published in: J Med Virol
October 1997
Partial genomic sequences of four hepatitis E virus (HEV) strains from Africa (Morocco and Tunisia) and one from Central Asia (Tashkent, Uzbekistan) were obtained. The reverse transcriptase-polymerase chain reaction was used to amplify 5' and hypervariable regions of open reading frame 1 (ORF1) and a region overlapping all 3 ORFs. Sequence analysis of these regions revealed the African strains to be quite distinct from all known Asian strains but more similar to them than to the Mexican strain. Sequence analysis of the Tashkent strain revealed almost complete identity with another central Asian strain from Osh, Kirgizia. These results thus further confirm the geographical origin of HEV strain divergence.
Duke Scholars
Published In
J Med Virol
ISSN
0146-6615
Publication Date
October 1997
Volume
53
Issue
2
Start / End Page
139 / 144
Location
United States
Related Subject Headings
- Virology
- Uzbekistan
- Tunisia
- Sequence Homology, Nucleic Acid
- Sequence Homology, Amino Acid
- Sequence Analysis, DNA
- Polymerase Chain Reaction
- Phylogeny
- Open Reading Frames
- Morocco
Citation
APA
Chicago
ICMJE
MLA
NLM
Chatterjee, R., Tsarev, S., Pillot, J., Coursaget, P., Emerson, S. U., & Purcell, R. H. (1997). African strains of hepatitis E virus that are distinct from Asian strains. J Med Virol, 53(2), 139–144.
Chatterjee, R., S. Tsarev, J. Pillot, P. Coursaget, S. U. Emerson, and R. H. Purcell. “African strains of hepatitis E virus that are distinct from Asian strains.” J Med Virol 53, no. 2 (October 1997): 139–44.
Chatterjee R, Tsarev S, Pillot J, Coursaget P, Emerson SU, Purcell RH. African strains of hepatitis E virus that are distinct from Asian strains. J Med Virol. 1997 Oct;53(2):139–44.
Chatterjee, R., et al. “African strains of hepatitis E virus that are distinct from Asian strains.” J Med Virol, vol. 53, no. 2, Oct. 1997, pp. 139–44.
Chatterjee R, Tsarev S, Pillot J, Coursaget P, Emerson SU, Purcell RH. African strains of hepatitis E virus that are distinct from Asian strains. J Med Virol. 1997 Oct;53(2):139–144.
Published In
J Med Virol
ISSN
0146-6615
Publication Date
October 1997
Volume
53
Issue
2
Start / End Page
139 / 144
Location
United States
Related Subject Headings
- Virology
- Uzbekistan
- Tunisia
- Sequence Homology, Nucleic Acid
- Sequence Homology, Amino Acid
- Sequence Analysis, DNA
- Polymerase Chain Reaction
- Phylogeny
- Open Reading Frames
- Morocco