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Molecular targets of anti-HIV-1 triterpenes.

Publication ,  Journal Article
Huang, L; Chen, CH
Published in: Curr Drug Targets Infect Disord
March 2002

Pentacyclic triterpenes have been found in many plants and may be isolated from any part of the plant. Triterpene derivatives were shown to have biological activities including anti-HIV-1 and anti-cancer activities. The modes of action of the anti-HIV-1 triterpenes have been reported to be associated with the virus entry, reverse transcription, virus assembly and maturation. This review will focus on the mechanisms of action of anti-HIV triterpenes and the structural features that contribute to their anti-HIV-1 activity and site of action.

Duke Scholars

Published In

Curr Drug Targets Infect Disord

DOI

ISSN

1568-0053

Publication Date

March 2002

Volume

2

Issue

1

Start / End Page

33 / 36

Location

Netherlands

Related Subject Headings

  • Virology
  • Triterpenes
  • Reverse Transcriptase Inhibitors
  • Receptors, Virus
  • Humans
  • HIV-1
  • HIV Protease Inhibitors
  • Anti-HIV Agents
 

Citation

APA
Chicago
ICMJE
MLA
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Huang, L., & Chen, C. H. (2002). Molecular targets of anti-HIV-1 triterpenes. Curr Drug Targets Infect Disord, 2(1), 33–36. https://doi.org/10.2174/1568005024605936
Huang, Li, and Chin Ho Chen. “Molecular targets of anti-HIV-1 triterpenes.Curr Drug Targets Infect Disord 2, no. 1 (March 2002): 33–36. https://doi.org/10.2174/1568005024605936.
Huang L, Chen CH. Molecular targets of anti-HIV-1 triterpenes. Curr Drug Targets Infect Disord. 2002 Mar;2(1):33–6.
Huang, Li, and Chin Ho Chen. “Molecular targets of anti-HIV-1 triterpenes.Curr Drug Targets Infect Disord, vol. 2, no. 1, Mar. 2002, pp. 33–36. Pubmed, doi:10.2174/1568005024605936.
Huang L, Chen CH. Molecular targets of anti-HIV-1 triterpenes. Curr Drug Targets Infect Disord. 2002 Mar;2(1):33–36.

Published In

Curr Drug Targets Infect Disord

DOI

ISSN

1568-0053

Publication Date

March 2002

Volume

2

Issue

1

Start / End Page

33 / 36

Location

Netherlands

Related Subject Headings

  • Virology
  • Triterpenes
  • Reverse Transcriptase Inhibitors
  • Receptors, Virus
  • Humans
  • HIV-1
  • HIV Protease Inhibitors
  • Anti-HIV Agents