Molecular targets of anti-HIV-1 triterpenes.
Journal Article (Journal Article;Review)
Pentacyclic triterpenes have been found in many plants and may be isolated from any part of the plant. Triterpene derivatives were shown to have biological activities including anti-HIV-1 and anti-cancer activities. The modes of action of the anti-HIV-1 triterpenes have been reported to be associated with the virus entry, reverse transcription, virus assembly and maturation. This review will focus on the mechanisms of action of anti-HIV triterpenes and the structural features that contribute to their anti-HIV-1 activity and site of action.
Full Text
Duke Authors
Cited Authors
- Huang, L; Chen, CH
Published Date
- March 2002
Published In
Volume / Issue
- 2 / 1
Start / End Page
- 33 - 36
PubMed ID
- 12462151
International Standard Serial Number (ISSN)
- 1568-0053
Digital Object Identifier (DOI)
- 10.2174/1568005024605936
Language
- eng
Conference Location
- Netherlands