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Motion and flow insensitive adiabatic T2 -preparation module for cardiac MR imaging at 3 Tesla.

Publication ,  Journal Article
Jenista, ER; Rehwald, WG; Chen, E-L; Kim, HW; Klem, I; Parker, MA; Kim, RJ
Published in: Magn Reson Med
November 2013

A versatile method for generating T2 -weighting is a T2 -preparation module, which has been used successfully for cardiac imaging at 1.5T. Although it has been applied at 3T, higher fields (B0 ≥ 3T) can degrade B0 and B1 homogeneity and result in nonuniform magnetization preparation. For cardiac imaging, blood flow and cardiac motion may further impair magnetization preparation. In this study, a novel T2 -preparation module containing multiple adiabatic B1 -insensitive refocusing pulses is introduced and compared with three previously described modules [(a) composite MLEV4, (b) modified BIR-4 (mBIR-4), and (c) Silver-Hoult-pair]. In the static phantom, the proposed module provided similar or better B0 and B1 insensitivity than the other modules. In human subjects (n = 21), quantitative measurement of image signal coefficient of variation, reflecting overall image inhomogeneity, was lower for the proposed module (0.10) than for MLEV4 (0.15, P < 0.0001), mBIR-4 (0.27, P < 0.0001), and Silver-Hoult-pair (0.14, P = 0.001) modules. Similarly, qualitative analysis revealed that the proposed module had the best image quality scores and ranking (both, P < 0.0001). In conclusion, we present a new T2 -preparation module, which is shown to be robust for cardiac imaging at 3T in comparison with existing methods.

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Published In

Magn Reson Med

DOI

EISSN

1522-2594

Publication Date

November 2013

Volume

70

Issue

5

Start / End Page

1360 / 1368

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • Reproducibility of Results
  • Nuclear Medicine & Medical Imaging
  • Movement
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging, Cine
  • Magnetic Resonance Angiography
  • Image Interpretation, Computer-Assisted
  • Image Enhancement
 

Citation

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Jenista, E. R., Rehwald, W. G., Chen, E.-L., Kim, H. W., Klem, I., Parker, M. A., & Kim, R. J. (2013). Motion and flow insensitive adiabatic T2 -preparation module for cardiac MR imaging at 3 Tesla. Magn Reson Med, 70(5), 1360–1368. https://doi.org/10.1002/mrm.24564
Jenista, Elizabeth R., Wolfgang G. Rehwald, Enn-Ling Chen, Han W. Kim, Igor Klem, Michele A. Parker, and Raymond J. Kim. “Motion and flow insensitive adiabatic T2 -preparation module for cardiac MR imaging at 3 Tesla.Magn Reson Med 70, no. 5 (November 2013): 1360–68. https://doi.org/10.1002/mrm.24564.
Jenista ER, Rehwald WG, Chen E-L, Kim HW, Klem I, Parker MA, et al. Motion and flow insensitive adiabatic T2 -preparation module for cardiac MR imaging at 3 Tesla. Magn Reson Med. 2013 Nov;70(5):1360–8.
Jenista, Elizabeth R., et al. “Motion and flow insensitive adiabatic T2 -preparation module for cardiac MR imaging at 3 Tesla.Magn Reson Med, vol. 70, no. 5, Nov. 2013, pp. 1360–68. Pubmed, doi:10.1002/mrm.24564.
Jenista ER, Rehwald WG, Chen E-L, Kim HW, Klem I, Parker MA, Kim RJ. Motion and flow insensitive adiabatic T2 -preparation module for cardiac MR imaging at 3 Tesla. Magn Reson Med. 2013 Nov;70(5):1360–1368.
Journal cover image

Published In

Magn Reson Med

DOI

EISSN

1522-2594

Publication Date

November 2013

Volume

70

Issue

5

Start / End Page

1360 / 1368

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • Reproducibility of Results
  • Nuclear Medicine & Medical Imaging
  • Movement
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging, Cine
  • Magnetic Resonance Angiography
  • Image Interpretation, Computer-Assisted
  • Image Enhancement