Use of quantitative CT to predict postoperative lung function in patients with lung cancer.


Journal Article

PURPOSE: To evaluate the effectiveness of quantitative computed tomography (CT) for predicting postoperative lung function in patients with lung cancer. MATERIALS AND METHODS: Preoperative spirometry and conventional CT of the chest were performed in 38 patients. A postprocessing CT program was applied to quantitate the volume of whole-lung parenchyma with attenuations of -500 to -910 HU; this was defined as total functional lung volume (TFLV). The regional functional lung volume (RFLV) of the lobes or lung to be resected was quantitated separately. CT-predicted postoperative forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) were derived by multiplying the preoperative spirometry values by (1 - RFLV/TFLV). RESULTS: CT-predicted values correlated well with postoperatively measured results (FEV1: r = .93, P < .001; FVC: r = .86, P < .001) in patients who underwent pneumonectomy or lobectomy, regardless of the patient's preoperative ventilation status. CONCLUSION: This method is effective in the prediction of postoperative FEV1 and FVC in patients undergoing pulmonary resection.

Full Text

Cited Authors

  • Wu, MT; Chang, JM; Chiang, AA; Lu, JY; Hsu, HK; Hsu, WH; Yang, CF

Published Date

  • April 1, 1994

Published In

Volume / Issue

  • 191 / 1

Start / End Page

  • 257 - 262

PubMed ID

  • 8134584

Pubmed Central ID

  • 8134584

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/radiology.191.1.8134584


  • eng

Conference Location

  • United States