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Applications of elastin-like polypeptides in tissue engineering.

Publication ,  Journal Article
Nettles, DL; Chilkoti, A; Setton, LA
Published in: Advanced drug delivery reviews
December 2010

Elastin-like polypeptides (ELPs) have found utility in tissue engineering applications, not only because they are biocompatible, biodegradable, and non-immunogenic, but also because their amino acid sequence and molecular weight can be precisely controlled at the genetic or synthetic level, affording exquisite control over final protein functionality. This review presents a basic overview of ELP properties and modifications that are relevant to tissue engineering, as well as a discussion of the application of ELPs to cartilage, intervertebral disc, vascular graft, liver, ocular, and cell sheet engineering.

Duke Scholars

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Published In

Advanced drug delivery reviews

DOI

EISSN

1872-8294

ISSN

0169-409X

Publication Date

December 2010

Volume

62

Issue

15

Start / End Page

1479 / 1485

Related Subject Headings

  • Tissue Engineering
  • Pharmacology & Pharmacy
  • Peptides
  • Humans
  • Elastin
  • 3214 Pharmacology and pharmaceutical sciences
  • 1115 Pharmacology and Pharmaceutical Sciences
 

Citation

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Nettles, D. L., Chilkoti, A., & Setton, L. A. (2010). Applications of elastin-like polypeptides in tissue engineering. Advanced Drug Delivery Reviews, 62(15), 1479–1485. https://doi.org/10.1016/j.addr.2010.04.002
Nettles, Dana L., Ashutosh Chilkoti, and Lori A. Setton. “Applications of elastin-like polypeptides in tissue engineering.Advanced Drug Delivery Reviews 62, no. 15 (December 2010): 1479–85. https://doi.org/10.1016/j.addr.2010.04.002.
Nettles DL, Chilkoti A, Setton LA. Applications of elastin-like polypeptides in tissue engineering. Advanced drug delivery reviews. 2010 Dec;62(15):1479–85.
Nettles, Dana L., et al. “Applications of elastin-like polypeptides in tissue engineering.Advanced Drug Delivery Reviews, vol. 62, no. 15, Dec. 2010, pp. 1479–85. Epmc, doi:10.1016/j.addr.2010.04.002.
Nettles DL, Chilkoti A, Setton LA. Applications of elastin-like polypeptides in tissue engineering. Advanced drug delivery reviews. 2010 Dec;62(15):1479–1485.
Journal cover image

Published In

Advanced drug delivery reviews

DOI

EISSN

1872-8294

ISSN

0169-409X

Publication Date

December 2010

Volume

62

Issue

15

Start / End Page

1479 / 1485

Related Subject Headings

  • Tissue Engineering
  • Pharmacology & Pharmacy
  • Peptides
  • Humans
  • Elastin
  • 3214 Pharmacology and pharmaceutical sciences
  • 1115 Pharmacology and Pharmaceutical Sciences