Endothelial cell growth on oxygen-containing films deposited by radio-frequency plasmas: the role of surface carbonyl groups.

Journal Article (Journal Article)

Polystyrene substrates were modified by radio-frequency plasma deposition from mixtures of various organic vapors (acetone, methane, methanol, and formic acid) and oxygen. The resulting surfaces exhibited a wide range of surface oxygen concentrations, as measured by electron spectroscopy for chemical analysis (ESCA). The surface hydroxyl, carboxyl, and carbonyl groups were derivatized with trifluoroacetic anhydride, trifluoroethanol, or hydrazine, respectively, and their concentrations subsequently determined by ESCA. The growth of bovine aortic endothelial cells was found to increase with the surface carbonyl concentration but did not appear to correlate with the hydroxyl or carboxyl concentrations.

Full Text

Duke Authors

Cited Authors

  • Ertel, SI; Chilkoti, A; Horbett, TA; Ratner, BD

Published Date

  • January 1, 1991

Published In

Volume / Issue

  • 3 / 2

Start / End Page

  • 163 - 183

PubMed ID

  • 1768637

Electronic International Standard Serial Number (EISSN)

  • 1568-5624

International Standard Serial Number (ISSN)

  • 0920-5063

Digital Object Identifier (DOI)

  • 10.1163/156856291x00269


  • eng