On stability designs in drug shelf-life estimation.
Journal Article (Journal Article)
In this paper, various stability designs, including matrixing and bracketing designs for determining drug shelf-life, are considered. We propose a criterion for design selection based on the precision of drug shelf-life estimates. For a fixed sample size, it is recommended that the design with the best precision for estimating the shelf-life should be used. For a fixed desired precision, the design with the smallest sample size is the best choice of design. An example is presented to illustrate the proposed method.
Full Text
Duke Authors
Cited Authors
- Ju, HL; Chow, SC
Published Date
- July 1995
Published In
Volume / Issue
- 5 / 2
Start / End Page
- 201 - 214
PubMed ID
- 7581428
International Standard Serial Number (ISSN)
- 1054-3406
Digital Object Identifier (DOI)
- 10.1080/10543409508835108
Language
- eng
Conference Location
- England