On stability designs in drug shelf-life estimation.

Journal Article (Journal Article)

In this paper, various stability designs, including matrixing and bracketing designs for determining drug shelf-life, are considered. We propose a criterion for design selection based on the precision of drug shelf-life estimates. For a fixed sample size, it is recommended that the design with the best precision for estimating the shelf-life should be used. For a fixed desired precision, the design with the smallest sample size is the best choice of design. An example is presented to illustrate the proposed method.

Full Text

Duke Authors

Cited Authors

  • Ju, HL; Chow, SC

Published Date

  • July 1995

Published In

Volume / Issue

  • 5 / 2

Start / End Page

  • 201 - 214

PubMed ID

  • 7581428

International Standard Serial Number (ISSN)

  • 1054-3406

Digital Object Identifier (DOI)

  • 10.1080/10543409508835108

Language

  • eng

Conference Location

  • England