Still Struggling: Characteristics of youth with OCD who are partial responders to medication treatment

Journal Article

The primary aim of this paper is to examine the characteristics of a large sample of youth with OCD who are partial responders (i.e., still have clinically significant symptoms) to serotonin reuptake inhibitor (SRI) medication. The sample will be described with regard to: demographics, treatment history, OCD symptoms/severity, family history and parental psychopathology, comorbidity, and global and family functioning. The sample includes 124 youth with OCD ranging in age from 7 to 17 with a primary diagnosis of OCD and a partial response to an SRI medication. The youth are a predominantly older (age 12 and over), Caucasian, middle to upper income group who had received significant past treatment. Key findings include moderate to severe OCD symptoms, high ratings of global impairment, and significant comorbidity, despite partial response to an adequate medication trial. Considerations regarding generalizability of the sample and limitations of the study are discussed. © Springer Science+Business Media, LLC 2011.

Full Text

Duke Authors

Cited Authors

  • Freeman, J; Sapyta, J; Garcia, A; Fitzgerald, D; Khanna, M; Choate-Summers, M; Moore, P; Chrisman, A; Haff, N; Naeem, A; March, J; Franklin, M

Published Date

  • 2011

Published In

Volume / Issue

  • 42 / 4

Start / End Page

  • 424 - 441

PubMed ID

  • 21484416

International Standard Serial Number (ISSN)

  • 0009-398X

Digital Object Identifier (DOI)

  • 10.1007/s10578-011-0227-4