Immunosuppressive activity of the retroviral envelope protein P 15E and its possible relationship to neoplasia.

Journal Article (Journal Article)

Type C retroviral infections can cause profound immunosuppression as well as neoplasms. The retroviral envelope protein p15E has both immunosuppressive and anti-inflammatory activities which may contribute to the pathogenicity of retroviruses. Murine and human neoplastic cells, not infected with retroviruses, have recently been found to contain p15E like antigens. In this article Ralph Snyderman and George Cianciolo discuss the potential relationship between p15E production, immunosuppression and neoplasia.

Full Text

Duke Authors

Cited Authors

  • Snyderman, R; Cianciolo, GJ

Published Date

  • August 1, 1984

Published In

Volume / Issue

  • 5 / 8

Start / End Page

  • 240 - 244

PubMed ID

  • 25290146

International Standard Serial Number (ISSN)

  • 0167-5699

Digital Object Identifier (DOI)

  • 10.1016/0167-5699(84)90097-5


  • eng

Conference Location

  • England