Under pressure: the search for the essential mechanisms of hypertension.
Journal Article (Journal Article;Review)
High blood pressure, or hypertension, is a very common disorder with a substantial impact on public health because of its associated complications. Despite the high prevalence of essential hypertension and years of research, the basic causes remain obscure. Here I review recent advances in understanding the pathophysiology of hypertension. I present a general overview of the field and, by necessity, use broad strokes to portray recent progress and place it in context. For this purpose, I use illustrative examples from the large number of important developments in hypertension research over the last five years. The intent of this review is to provide a sense of where the field is progressing, with an emphasis on work that sheds light on pathogenic mechanisms and that is therefore likely to inform new translational advances.
- Coffman, TM
- November 7, 2011
Volume / Issue
- 17 / 11
Start / End Page
- 1402 - 1409
Electronic International Standard Serial Number (EISSN)
Digital Object Identifier (DOI)
- United States