The roles of anxiety and depression in connecting tic severity and functional impairment.


Journal Article

The current study examined relationships between tic severity and both functional impairment and perceived quality of life (QOL) in adults with a chronic tic disorder. The authors explored whether these relationships were moderated by anxiety and depressive symptoms. Five-hundred adults with Tourette's Disorder, Chronic Motor Tic Disorder, or Chronic Vocal Tic Disorder participated in a comprehensive self-report internet-based survey. Anxiety and depressive symptoms moderated the relationship between tic severity and functional impairment such that stronger relationships were documented in participants with elevated depressive or anxious symptoms. Limitations and implications for research and clinical practice are discussed.

Full Text

Duke Authors

Cited Authors

  • Lewin, AB; Storch, EA; Conelea, CA; Woods, DW; Zinner, SH; Budman, CL; Scahill, LD; Compton, SN; Walkup, JT; Murphy, TK

Published Date

  • March 2011

Published In

Volume / Issue

  • 25 / 2

Start / End Page

  • 164 - 168

PubMed ID

  • 20889290

Pubmed Central ID

  • 20889290

Electronic International Standard Serial Number (EISSN)

  • 1873-7897

Digital Object Identifier (DOI)

  • 10.1016/j.janxdis.2010.08.016


  • eng

Conference Location

  • Netherlands