Skip to main content
Journal cover image

Memory impairment in elderly individuals with a mildly elevated serum TSH: The role of processing resources, depression and cerebrovascular disease

Publication ,  Journal Article
Cook, SE; Nebes, RD; Halligan, EM; Burmeister, LA; Saxton, JA; Ganguli, M; Fukui, MB; Meltzer, CC; Williams, RL; DeKosky, ST
Published in: Aging, Neuropsychology, and Cognition
September 1, 2002

This study examined whether a mild elevation in serum Thyroid Stimulating Hormone (TSH) in normal older individuals was associated with a cognitive impairment. Participants consisted of 15 individuals with a high-TSH level and 82 with a normal TSH. The high-TSH group performed significantly worse than the normal-TSH group of tests of immediate and delayed verbal recall and on the Mini-Mental State Exam. This decrement was not due to group differences in processing resources nor was it explained by comorbid cerebrovascular disease, depression or anticholinergic drug usage. These results suggest that undetected mild thyroid dysfunction may contribute to the cognitive decrements found in older adults.

Duke Scholars

Published In

Aging, Neuropsychology, and Cognition

DOI

ISSN

1382-5585

Publication Date

September 1, 2002

Volume

9

Issue

3

Start / End Page

175 / 183

Related Subject Headings

  • Experimental Psychology
  • 52 Psychology
  • 1702 Cognitive Sciences
  • 1701 Psychology
  • 1109 Neurosciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Cook, S. E., Nebes, R. D., Halligan, E. M., Burmeister, L. A., Saxton, J. A., Ganguli, M., … DeKosky, S. T. (2002). Memory impairment in elderly individuals with a mildly elevated serum TSH: The role of processing resources, depression and cerebrovascular disease. Aging, Neuropsychology, and Cognition, 9(3), 175–183. https://doi.org/10.1076/anec.9.3.175.9610
Cook, S. E., R. D. Nebes, E. M. Halligan, L. A. Burmeister, J. A. Saxton, M. Ganguli, M. B. Fukui, C. C. Meltzer, R. L. Williams, and S. T. DeKosky. “Memory impairment in elderly individuals with a mildly elevated serum TSH: The role of processing resources, depression and cerebrovascular disease.” Aging, Neuropsychology, and Cognition 9, no. 3 (September 1, 2002): 175–83. https://doi.org/10.1076/anec.9.3.175.9610.
Cook SE, Nebes RD, Halligan EM, Burmeister LA, Saxton JA, Ganguli M, et al. Memory impairment in elderly individuals with a mildly elevated serum TSH: The role of processing resources, depression and cerebrovascular disease. Aging, Neuropsychology, and Cognition. 2002 Sep 1;9(3):175–83.
Cook, S. E., et al. “Memory impairment in elderly individuals with a mildly elevated serum TSH: The role of processing resources, depression and cerebrovascular disease.” Aging, Neuropsychology, and Cognition, vol. 9, no. 3, Sept. 2002, pp. 175–83. Scopus, doi:10.1076/anec.9.3.175.9610.
Cook SE, Nebes RD, Halligan EM, Burmeister LA, Saxton JA, Ganguli M, Fukui MB, Meltzer CC, Williams RL, DeKosky ST. Memory impairment in elderly individuals with a mildly elevated serum TSH: The role of processing resources, depression and cerebrovascular disease. Aging, Neuropsychology, and Cognition. 2002 Sep 1;9(3):175–183.
Journal cover image

Published In

Aging, Neuropsychology, and Cognition

DOI

ISSN

1382-5585

Publication Date

September 1, 2002

Volume

9

Issue

3

Start / End Page

175 / 183

Related Subject Headings

  • Experimental Psychology
  • 52 Psychology
  • 1702 Cognitive Sciences
  • 1701 Psychology
  • 1109 Neurosciences