Telomeres and telomerase in human cancer (review).

Journal Article (Journal Article)

Telomerase has recently come into the limelight as one of the most prevalent tumour markers, due to its nearly ubiquitous presence in malignant tissues and absence from most somatic tissues. The essential role of telomeres in unlimited cell proliferation and that of the enzyme in telomere maintenance have suggested that telomerase inhibitors may be effective in cancer therapy. We provide here a compendium and an evaluation of the available data relating to this hypothesis.

Full Text

Duke Authors

Cited Authors

  • Bacchetti, S; Counter, C

Published Date

  • September 1995

Published In

Volume / Issue

  • 7 / 3

Start / End Page

  • 423 - 432

PubMed ID

  • 21552856

International Standard Serial Number (ISSN)

  • 1019-6439


  • eng

Conference Location

  • Greece