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Chemical amplification with encapsulated reagents.

Publication ,  Journal Article
Chen, J; Körner, S; Craig, SL; Lin, S; Rudkevich, DM; Rebek, J
Published in: Proceedings of the National Academy of Sciences of the United States of America
March 2002

Autocatalysis and chemical amplification are characteristic properties of living systems, and they give rise to behaviors such as increased sensitivity, responsiveness, and self-replication. Here we report a synthetic system in which a unique form of compartmentalization leads to nonlinear, autocatalytic behavior. The compartment is a reversibly formed capsule in which a reagent is sequestered. Reaction products displace the reagent from the capsule into solution and the reaction rate is accelerated. The resulting self-regulation is sensitive to the highly selective molecular recognition properties of the capsule.

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Published In

Proceedings of the National Academy of Sciences of the United States of America

DOI

EISSN

1091-6490

ISSN

0027-8424

Publication Date

March 2002

Volume

99

Issue

5

Start / End Page

2593 / 2596
 

Citation

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Chen, J., Körner, S., Craig, S. L., Lin, S., Rudkevich, D. M., & Rebek, J. (2002). Chemical amplification with encapsulated reagents. Proceedings of the National Academy of Sciences of the United States of America, 99(5), 2593–2596. https://doi.org/10.1073/pnas.052706499
Chen, Jian, Steffi Körner, Stephen L. Craig, Shirley Lin, Dmitry M. Rudkevich, and Julius Rebek. “Chemical amplification with encapsulated reagents.Proceedings of the National Academy of Sciences of the United States of America 99, no. 5 (March 2002): 2593–96. https://doi.org/10.1073/pnas.052706499.
Chen J, Körner S, Craig SL, Lin S, Rudkevich DM, Rebek J. Chemical amplification with encapsulated reagents. Proceedings of the National Academy of Sciences of the United States of America. 2002 Mar;99(5):2593–6.
Chen, Jian, et al. “Chemical amplification with encapsulated reagents.Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 5, Mar. 2002, pp. 2593–96. Epmc, doi:10.1073/pnas.052706499.
Chen J, Körner S, Craig SL, Lin S, Rudkevich DM, Rebek J. Chemical amplification with encapsulated reagents. Proceedings of the National Academy of Sciences of the United States of America. 2002 Mar;99(5):2593–2596.
Journal cover image

Published In

Proceedings of the National Academy of Sciences of the United States of America

DOI

EISSN

1091-6490

ISSN

0027-8424

Publication Date

March 2002

Volume

99

Issue

5

Start / End Page

2593 / 2596