Late thrombosis following treatment of in-stent restenosis with drug-eluting stents after discontinuation of antiplatelet therapy.

Journal Article (Journal Article)

Drug-eluting stent usage has become commonplace for the percutaneous treatment of de novo coronary lesions, but the safety and efficacy profile for their evolving usage in restenotic lesions is largely unknown. We report three cases of angiographically confirmed drug-eluting stent thrombosis following treatment of restenotic lesions that occurred late (193, 237, and 535 days) and shortly after interruption of antiplatelet therapy. All three patients suffered ST elevation myocardial infarction, and there was one death. Further studies are necessary to better define the associated risk and ideal duration of antiplatelet therapy necessary in this cohort of patients with restenotic lesions.

Full Text

Duke Authors

Cited Authors

  • Waters, RE; Kandzari, DE; Phillips, HR; Crawford, LE; Sketch, MH

Published Date

  • August 2005

Published In

Volume / Issue

  • 65 / 4

Start / End Page

  • 520 - 524

PubMed ID

  • 15973673

International Standard Serial Number (ISSN)

  • 1522-1946

Digital Object Identifier (DOI)

  • 10.1002/ccd.20428


  • eng

Conference Location

  • United States