Fe(III)-complexes of the tripodal trishydroxamate siderophore basidiochrome: potential biological implications.

Published

Journal Article

One method of mobilization of iron by mycorrhizal organisms is through the secretion of small organic chelators called siderophores. Hydroxamate donor chelators are a common type of siderophore that is frequently used by fungal organisms. The primary siderophore that is produced by fungi from the genera Ceratobasidium and Rhizoctonia is the tripodal trishydroxamate siderophore basidiochrome. To gain some insight into the iron uptake mechanisms of these symbiotic fungi, the iron binding characteristics of basidiochrome were determined. It was found that basidiochrome exhibits a log β(110) of 27.8±0.1 and a pFe value of 25.0. These values are similar to those of another fungal trishydroxamate siderophore, ferrichrome. The similarity in iron affinity between the two siderophores suggests that the structure of the backbone has little influence in complex formation due to the length of the pendant arms, although the identity of the terminating groups of the pendant arms is likely related to complex stability. The role of basidiochrome in the biogeochemical cycling of iron is also discussed.

Full Text

Duke Authors

Cited Authors

  • Harrington, JM; Winkelmann, G; Haselwandter, K; Crumbliss, AL

Published Date

  • December 2011

Published In

Volume / Issue

  • 105 / 12

Start / End Page

  • 1670 - 1674

PubMed ID

  • 22079978

Pubmed Central ID

  • 22079978

Electronic International Standard Serial Number (EISSN)

  • 1873-3344

International Standard Serial Number (ISSN)

  • 0162-0134

Digital Object Identifier (DOI)

  • 10.1016/j.jinorgbio.2011.08.010

Language

  • eng