Siderophore-redox active ionophore host-guest assemblies: A prototype for selective metal ion compartmentalization

Published

Journal Article

The reduction potentials for two Wurster's crowns, aza crown ethers which incorporate the redox active N,N,N′,N′-tetraalkyl-1,4- phenylenediamine into the structure of 18-crown-6, were studied in the presence of the siderophore ferrioxamine B, FeHDFB+. Addition of FeHDFB + resulted in a positive shift in the host reduction potential for both aza crown ethers studied. This shift is explained in terms of host-guest supramolecular assembly formation, which was independently verified by FAB-MS. An enhanced affinity for host-guest formation of the reduced aza crown ether was calculated for each aza crown ether-siderophore assembly using a thermochemical cycle. These differences in host binding affinity as a function of redox state can be harnessed for use in specific metal ion compartmentalization with application, for example, to environmental remediation. © 2010 Elsevier B.V. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Tristani, EM; Wirgau, JI; Dubay, GR; Sibert, JW; Crumbliss, AL

Published Date

  • October 25, 2010

Published In

Volume / Issue

  • 363 / 13

Start / End Page

  • 3611 - 3615

International Standard Serial Number (ISSN)

  • 0020-1693

Digital Object Identifier (DOI)

  • 10.1016/j.ica.2010.05.052

Citation Source

  • Scopus