Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm

Journal Article (Review;Journal)

The siderophore-mediated iron transport in A. hydrophila was found to occur by means of a siderophore transport system with a very low specificity. At least two groups of transport systems were found to be present in A. hydrophila, of which one of them was indiscriminant towards a series of iron-siderophore complexes and iron complexes of siderophore analogs. The Fe(III) uptake proceeds via a redox-free ligand exchange mechanism in which iron from an iron-siderophore complex exchanges with a receptor-bound apo-siderophore. This exchange process is believed to be proton driven and is triggered by a pH gradient inside the β-barrel of the receptor.

Duke Authors

Cited Authors

  • Dhungana, S; Crumbliss, AL

Published Date

  • August 6, 2001

Published In

Volume / Issue

  • 14 / 5

Start / End Page

  • 258 - 265

International Standard Serial Number (ISSN)

  • 1431-9268

Citation Source

  • Scopus