Direct electron transfer at horseradish peroxidase-colloidal gold modified electrodes

Journal Article (Journal Article)

The reduction of H2O2 on horseradish peroxidase (HRP) and horseradish peroxidase-gold sol (HRP-Au) modified electrodes has been studied with and without an electron transfer mediator. The amplification effect owing to the enzyme-catalyzed turnover of substrate facilitates our observation that HRP immobilized on colloidal gold and then deposited on a flat electrode surface can be reduced at a convenient rate at 0 V (Ag/AgCl) without an electron transfer mediator. Possible mechanisms and potential applications are discussed. © 1992.

Full Text

Duke Authors

Cited Authors

  • Zhao, J; Henkens, RW; Stonehuerner, J; O'Daly, JP; Crumbliss, AL

Published Date

  • June 10, 1992

Published In

Volume / Issue

  • 327 / 1-2

Start / End Page

  • 109 - 119

International Standard Serial Number (ISSN)

  • 0022-0728

Digital Object Identifier (DOI)

  • 10.1016/0022-0728(92)80140-Y

Citation Source

  • Scopus