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Canalicular reticulum in vestibular hair cells.

Publication ,  Journal Article
Cunningham, CD; Weber, PC; Spicer, SS; Schulte, BA
Published in: Hear Res
May 2000

A membrane limited system referred to as canalicular reticulum (CR) has been demonstrated in the apical cytosol of the cochlea's inner and outer hair cells. Similarities between cochlear and vestibular hair cells prompted investigation of the presence of CR in hair cells of the gerbil vestibular labyrinth. A method of fixation with glutaraldehyde followed by an osmium-ferrocyanide mixture demonstrated abundant CR in the apex of both type I and type II hair cells. The CR was closely associated with numerous Golgi zones in the apex of the vestibular hair cells, indicating its genesis from Golgi cisternae. Also preserved in upper cytosol were discrete complexes of mitochondria with granular reticulum. These complexes offered a possible site for generating the membrane in Golgi zones and CR. Single and parallel cisternae of granular reticulum were observed in the basal half of the hair cells together with numerous synaptic-like vesicles. These cisternae with their terminal blebbing and accompanying canaliculi were interpreted as novel structures mediating synaptic vesicle genesis in vestibular hair cells in a manner comparable to that postulated for cochlear inner hair cells.

Duke Scholars

Published In

Hear Res

DOI

ISSN

0378-5955

Publication Date

May 2000

Volume

143

Issue

1-2

Start / End Page

69 / 83

Location

Netherlands

Related Subject Headings

  • Vestibule, Labyrinth
  • Otorhinolaryngology
  • Mitochondria
  • Microscopy, Electron
  • Hair Cells, Auditory
  • Golgi Apparatus
  • Gerbillinae
  • Endoplasmic Reticulum
  • Animals
  • 5202 Biological psychology
 

Citation

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ICMJE
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Cunningham, C. D., Weber, P. C., Spicer, S. S., & Schulte, B. A. (2000). Canalicular reticulum in vestibular hair cells. Hear Res, 143(1–2), 69–83. https://doi.org/10.1016/s0378-5955(00)00022-8
Cunningham, C. D., P. C. Weber, S. S. Spicer, and B. A. Schulte. “Canalicular reticulum in vestibular hair cells.Hear Res 143, no. 1–2 (May 2000): 69–83. https://doi.org/10.1016/s0378-5955(00)00022-8.
Cunningham CD, Weber PC, Spicer SS, Schulte BA. Canalicular reticulum in vestibular hair cells. Hear Res. 2000 May;143(1–2):69–83.
Cunningham, C. D., et al. “Canalicular reticulum in vestibular hair cells.Hear Res, vol. 143, no. 1–2, May 2000, pp. 69–83. Pubmed, doi:10.1016/s0378-5955(00)00022-8.
Cunningham CD, Weber PC, Spicer SS, Schulte BA. Canalicular reticulum in vestibular hair cells. Hear Res. 2000 May;143(1–2):69–83.
Journal cover image

Published In

Hear Res

DOI

ISSN

0378-5955

Publication Date

May 2000

Volume

143

Issue

1-2

Start / End Page

69 / 83

Location

Netherlands

Related Subject Headings

  • Vestibule, Labyrinth
  • Otorhinolaryngology
  • Mitochondria
  • Microscopy, Electron
  • Hair Cells, Auditory
  • Golgi Apparatus
  • Gerbillinae
  • Endoplasmic Reticulum
  • Animals
  • 5202 Biological psychology