Subfunctionalization: How often does it occur? How long does it take?
Journal Article (Journal Article)
The mechanisms responsible for the preservation of duplicate genes have been debated for more than 70 years. Recently, Lynch and Force have proposed a new explanation: subfunctionalization--after duplication the two gene copies specialize to perform complementary functions. We investigate the probability that subfunctionalization occurs, the amount of time after duplication that it takes for the outcome to be resolved, and the relationship of these quantities to the population size and mutation rates.
Full Text
Duke Authors
Cited Authors
- Ward, R; Durrett, R
Published Date
- September 2004
Published In
Volume / Issue
- 66 / 2
Start / End Page
- 93 - 100
PubMed ID
- 15302219
Electronic International Standard Serial Number (EISSN)
- 1096-0325
International Standard Serial Number (ISSN)
- 0040-5809
Digital Object Identifier (DOI)
- 10.1016/j.tpb.2004.03.004
Language
- eng