Gene expression signatures and outcome prediction in mature B-cell malignancies.

Journal Article (Review)

Non-Hodgkin's lymphomas comprise a diverse group of diseases that are subclassified by the state of differentiation of the malignant B cells, presence of specific cytogenetic abnormalities, and characteristic morphology. Gene expression profiling has revealed that within each category of non-Hodgkin's lymphoma, there exists a significant molecular heterogeneity that can be reflected in differences in tumor behavior and patient outcome. Appreciation of gene expression signatures that are associated with patient outcome will allow better prognostication of disease course and aid the application of molecularly selective patients to improve patient outcome.

Full Text

Duke Authors

Cited Authors

  • Dave, SS

Published Date

  • July 2006

Published In

Volume / Issue

  • 7 / 4

Start / End Page

  • 261 - 269

PubMed ID

  • 16916486

International Standard Serial Number (ISSN)

  • 1527-2729

Language

  • eng

Conference Location

  • United States