Demographic, maltreatment, and neurobiological correlates of PTSD symptoms in children and adolescents.

Published

Journal Article

To examine the relationships of demographic, maltreatment, neurostructural and neuropsychological measures with total posttraumatic stress disorder (PTSD) symptoms.Participants included 216 children with maltreatment histories (N = 49), maltreatment and PTSD (N = 49), or no maltreatment (N = 118). Participants received diagnostic interviews, brain imaging, and neuropsychological evaluations.We examined a hierarchical regression model comprised of independent variables including demographics, trauma and maltreatment-related variables, and hippocampal volumes and neuropsychological measures to model PTSD symptoms. Important independent contributors to this model were SES, and General Maltreatment and Sexual Abuse Factors. Although hippocampal volumes were not significant, Visual Memory was a significant contributor to this model.Similar to adult PTSD, pediatric PTSD symptoms are associated with lower Visual Memory performance. It is an important correlate of PTSD beyond established predictors of PTSD symptoms. These results support models of developmental traumatology and suggest that treatments which enhance visual memory may decrease symptoms of PTSD.

Full Text

Duke Authors

Cited Authors

  • De Bellis, MD; Hooper, SR; Woolley, DP; Shenk, CE

Published Date

  • June 2010

Published In

Volume / Issue

  • 35 / 5

Start / End Page

  • 570 - 577

PubMed ID

  • 20008084

Pubmed Central ID

  • 20008084

Electronic International Standard Serial Number (EISSN)

  • 1465-735X

International Standard Serial Number (ISSN)

  • 0146-8693

Digital Object Identifier (DOI)

  • 10.1093/jpepsy/jsp116

Language

  • eng