Flow cytometry in pediatric immunologic disorders

Lymphocyte phenotyping by flow cytometric methods has become a standard tool for evaluating infants and children for primary or secondary immunodeficiency disorders. Flow technology is additionally attractive for pediatric use since sample requirements are minimal. Despite these technological advances, greater potential exists in flow cytometric applications which have not yet been extensively explored. For example, greater use of available monoclonal antibodies in multiparameter studies is accessible and desirable to better understand the pathogenesis of pediatric immune disorders. With these studies, we hope that new or improved therapies will emerge. © 1991.

Duke Scholars

Author Thomas Norton Denny Medicine, Duke Human Vaccine Institute