Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus).
Publication
, Journal Article
Gallagher, EP; Di Giulio, RT
Published in: Toxicology letters
June 1991
Channel catfish (Ictalurus punctatus) exposed to a mixture of picloram and 2,4-dichlorophenoxyacetic acid (2,4-D) for 10 days displayed increased activities of hepatic ethoxyresorufin O-deethylase (EROD), decreased serum chloride concentrations and decreased liver/body weight ratios. These changes were not observed in fish exposed to either compound alone. Neither compound, nor their mixture, increased hepatic peroxisomal catalase or lauroyl CoA oxidase activities. The results of this study indicate that 10-day exposure of 2,4-D or picloram does not induce peroxisomal enzymes in channel catfish; however, exposure to a mixture of 2,4-D and picloram may cause physiological effects to catfish not observed with either compound alone.
Duke Scholars
Published In
Toxicology letters
DOI
EISSN
1879-3169
ISSN
0378-4274
Publication Date
June 1991
Volume
57
Issue
1
Start / End Page
65 / 72
Related Subject Headings
- Toxicology
- Picloram
- Oxidoreductases
- Organ Size
- Microbodies
- Liver
- Ictaluridae
- Glutathione Transferase
- Cytochrome P-450 Enzyme System
- Cytochrome P-450 CYP1A1
Citation
APA
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ICMJE
MLA
NLM
Gallagher, E. P., & Di Giulio, R. T. (1991). Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus). Toxicology Letters, 57(1), 65–72. https://doi.org/10.1016/0378-4274(91)90120-u
Gallagher, E. P., and R. T. Di Giulio. “Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus).” Toxicology Letters 57, no. 1 (June 1991): 65–72. https://doi.org/10.1016/0378-4274(91)90120-u.
Gallagher EP, Di Giulio RT. Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus). Toxicology letters. 1991 Jun;57(1):65–72.
Gallagher, E. P., and R. T. Di Giulio. “Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus).” Toxicology Letters, vol. 57, no. 1, June 1991, pp. 65–72. Epmc, doi:10.1016/0378-4274(91)90120-u.
Gallagher EP, Di Giulio RT. Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus). Toxicology letters. 1991 Jun;57(1):65–72.
Published In
Toxicology letters
DOI
EISSN
1879-3169
ISSN
0378-4274
Publication Date
June 1991
Volume
57
Issue
1
Start / End Page
65 / 72
Related Subject Headings
- Toxicology
- Picloram
- Oxidoreductases
- Organ Size
- Microbodies
- Liver
- Ictaluridae
- Glutathione Transferase
- Cytochrome P-450 Enzyme System
- Cytochrome P-450 CYP1A1