Hepatic complications of obesity.


Journal Article (Review)

Obesity is associated with a spectrum of chronic liver disease. Because obesity increases the risk for advanced forms of liver disease (ie, cirrhosis and liver cancer), the obesity epidemic is emerging as a major factor underlying the burden of liver disease in the United States and many other countries. This article reviews mechanisms that mediate the pathogenesis of obesity-related liver disease, summarizes clinical evidence that demonstrates obesity-related liver disease can be life-threatening, and discusses whether or not treatments for obesity or related comorbidities impact liver disease outcomes.

Full Text

Duke Authors

Cited Authors

  • Diehl, AM

Published Date

  • March 2010

Published In

Volume / Issue

  • 39 / 1

Start / End Page

  • 57 - 68

PubMed ID

  • 20202579

Pubmed Central ID

  • 20202579

Electronic International Standard Serial Number (EISSN)

  • 1558-1942

Digital Object Identifier (DOI)

  • 10.1016/j.gtc.2009.12.001


  • eng

Conference Location

  • United States