Skip to main content

Nonalcoholic Steatohepatitis.

Publication ,  Journal Article
Suzuki, A; Diehl, AM
Published in: Annu Rev Med
January 14, 2017

Nonalcoholic steatohepatitis (NASH) has become a major cause of cirrhosis and liver-related deaths worldwide. NASH is strongly associated with obesity and the metabolic syndrome, conditions that cause lipid accumulation in hepatocytes (hepatic steatosis). It is not well understood why some, but not other, individuals with hepatic steatosis develop NASH. The factors that determine whether or not NASH progresses to cirrhosis are also unclear. This review summarizes key components of NASH pathogenesis and discusses how inherent and acquired variations in regulation of these processes impact the risk for NASH and NASH cirrhosis.

Duke Scholars

Published In

Annu Rev Med

DOI

EISSN

1545-326X

Publication Date

January 14, 2017

Volume

68

Start / End Page

85 / 98

Location

United States

Related Subject Headings

  • Non-alcoholic Fatty Liver Disease
  • Liver Cirrhosis
  • Liver
  • Lipid Metabolism
  • Humans
  • Hepatocytes
  • Hepatitis
  • General & Internal Medicine
  • Cell Death
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Suzuki, A., & Diehl, A. M. (2017). Nonalcoholic Steatohepatitis. Annu Rev Med, 68, 85–98. https://doi.org/10.1146/annurev-med-051215-031109
Suzuki, Ayako, and Anna Mae Diehl. “Nonalcoholic Steatohepatitis.Annu Rev Med 68 (January 14, 2017): 85–98. https://doi.org/10.1146/annurev-med-051215-031109.
Suzuki A, Diehl AM. Nonalcoholic Steatohepatitis. Annu Rev Med. 2017 Jan 14;68:85–98.
Suzuki, Ayako, and Anna Mae Diehl. “Nonalcoholic Steatohepatitis.Annu Rev Med, vol. 68, Jan. 2017, pp. 85–98. Pubmed, doi:10.1146/annurev-med-051215-031109.
Suzuki A, Diehl AM. Nonalcoholic Steatohepatitis. Annu Rev Med. 2017 Jan 14;68:85–98.

Published In

Annu Rev Med

DOI

EISSN

1545-326X

Publication Date

January 14, 2017

Volume

68

Start / End Page

85 / 98

Location

United States

Related Subject Headings

  • Non-alcoholic Fatty Liver Disease
  • Liver Cirrhosis
  • Liver
  • Lipid Metabolism
  • Humans
  • Hepatocytes
  • Hepatitis
  • General & Internal Medicine
  • Cell Death
  • 3202 Clinical sciences