Nonalcoholic Steatohepatitis.
Publication
, Journal Article
Suzuki, A; Diehl, AM
Published in: Annu Rev Med
January 14, 2017
Nonalcoholic steatohepatitis (NASH) has become a major cause of cirrhosis and liver-related deaths worldwide. NASH is strongly associated with obesity and the metabolic syndrome, conditions that cause lipid accumulation in hepatocytes (hepatic steatosis). It is not well understood why some, but not other, individuals with hepatic steatosis develop NASH. The factors that determine whether or not NASH progresses to cirrhosis are also unclear. This review summarizes key components of NASH pathogenesis and discusses how inherent and acquired variations in regulation of these processes impact the risk for NASH and NASH cirrhosis.
Duke Scholars
Published In
Annu Rev Med
DOI
EISSN
1545-326X
Publication Date
January 14, 2017
Volume
68
Start / End Page
85 / 98
Location
United States
Related Subject Headings
- Non-alcoholic Fatty Liver Disease
- Liver Cirrhosis
- Liver
- Lipid Metabolism
- Humans
- Hepatocytes
- Hepatitis
- General & Internal Medicine
- Cell Death
- 3202 Clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Suzuki, A., & Diehl, A. M. (2017). Nonalcoholic Steatohepatitis. Annu Rev Med, 68, 85–98. https://doi.org/10.1146/annurev-med-051215-031109
Suzuki, Ayako, and Anna Mae Diehl. “Nonalcoholic Steatohepatitis.” Annu Rev Med 68 (January 14, 2017): 85–98. https://doi.org/10.1146/annurev-med-051215-031109.
Suzuki A, Diehl AM. Nonalcoholic Steatohepatitis. Annu Rev Med. 2017 Jan 14;68:85–98.
Suzuki, Ayako, and Anna Mae Diehl. “Nonalcoholic Steatohepatitis.” Annu Rev Med, vol. 68, Jan. 2017, pp. 85–98. Pubmed, doi:10.1146/annurev-med-051215-031109.
Suzuki A, Diehl AM. Nonalcoholic Steatohepatitis. Annu Rev Med. 2017 Jan 14;68:85–98.
Published In
Annu Rev Med
DOI
EISSN
1545-326X
Publication Date
January 14, 2017
Volume
68
Start / End Page
85 / 98
Location
United States
Related Subject Headings
- Non-alcoholic Fatty Liver Disease
- Liver Cirrhosis
- Liver
- Lipid Metabolism
- Humans
- Hepatocytes
- Hepatitis
- General & Internal Medicine
- Cell Death
- 3202 Clinical sciences