Genomic signatures in non-small-cell lung cancer: targeting the targeted therapies.


Journal Article (Review)

Despite major developments in targeted biologic agents, patients with advanced non-small-cell lung cancer have a poor prognosis. Recent development of targeted biologic agents have given us insight into possibilities of matching therapy with disease; however, the success of these agents has been marginal. In this article, we discuss the use of genomic signatures that have been developed to identify unique aspects of individual lung tumors and provide insight on how novel strategies can be used to identify populations susceptible to specific targeted agents.

Full Text

Duke Authors

Cited Authors

  • Dressman, HK; Bild, A; Garst, J; Harpole, D; Potti, A

Published Date

  • July 2006

Published In

Volume / Issue

  • 8 / 4

Start / End Page

  • 252 - 257

PubMed ID

  • 17254524

Pubmed Central ID

  • 17254524

International Standard Serial Number (ISSN)

  • 1523-3790


  • eng

Conference Location

  • United States