Skip to main content
Journal cover image

Improving risk Assessment: Research opportunities in dose response modeling to improve risk assessment

Publication ,  Journal Article
Zeise, L; Hattis, D; Andersen, M; Bailer, AJ; Bayard, S; Chen, C; Clewell, H; Conolly, R; Crump, K; Dunson, D; Finkel, A; Haber, L; Kodell, R ...
Published in: Human and Ecological Risk Assessment
October 1, 2002

Substantial improvements in dose response modeling for risk assessment may result from recent and continuing advances in biological research, biochemical techniques, biostatistical/mathematical methods and computational power. This report provides a ranked set of recommendations for proposed research to advance the state of the art in dose response modeling. The report is the result of a meeting of invited workgroup participants charged with identifying five areas of research in dose response modeling that could be incorporated in a national agenda to improve risk assessment methods. Leading topics of emphasis are interindividual variability, injury risk assessment modeling, and procedures to incorporate distributional methods and mechanistic considerations into now-standard methods of deriving a reference dose (RfD), reference concentration (RfC), minimum risk level (MRL) or similar dose-response parameter estimates. © 2002 by ASP.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Human and Ecological Risk Assessment

DOI

ISSN

1080-7039

Publication Date

October 1, 2002

Volume

8

Issue

6

Start / End Page

1421 / 1444

Related Subject Headings

  • Strategic, Defence & Security Studies
  • 4105 Pollution and contamination
  • 4104 Environmental management
  • 0602 Ecology
  • 0502 Environmental Science and Management
  • 0501 Ecological Applications
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Zeise, L., Hattis, D., Andersen, M., Bailer, A. J., Bayard, S., Chen, C., … Wassell, J. T. (2002). Improving risk Assessment: Research opportunities in dose response modeling to improve risk assessment. Human and Ecological Risk Assessment, 8(6), 1421–1444. https://doi.org/10.1080/20028091057448
Zeise, L., D. Hattis, M. Andersen, A. J. Bailer, S. Bayard, C. Chen, H. Clewell, et al. “Improving risk Assessment: Research opportunities in dose response modeling to improve risk assessment.” Human and Ecological Risk Assessment 8, no. 6 (October 1, 2002): 1421–44. https://doi.org/10.1080/20028091057448.
Zeise L, Hattis D, Andersen M, Bailer AJ, Bayard S, Chen C, et al. Improving risk Assessment: Research opportunities in dose response modeling to improve risk assessment. Human and Ecological Risk Assessment. 2002 Oct 1;8(6):1421–44.
Zeise, L., et al. “Improving risk Assessment: Research opportunities in dose response modeling to improve risk assessment.” Human and Ecological Risk Assessment, vol. 8, no. 6, Oct. 2002, pp. 1421–44. Scopus, doi:10.1080/20028091057448.
Zeise L, Hattis D, Andersen M, Bailer AJ, Bayard S, Chen C, Clewell H, Conolly R, Crump K, Dunson D, Finkel A, Haber L, Jarabek AM, Kodell R, Krewski D, Thomas D, Thorslund T, Wassell JT. Improving risk Assessment: Research opportunities in dose response modeling to improve risk assessment. Human and Ecological Risk Assessment. 2002 Oct 1;8(6):1421–1444.
Journal cover image

Published In

Human and Ecological Risk Assessment

DOI

ISSN

1080-7039

Publication Date

October 1, 2002

Volume

8

Issue

6

Start / End Page

1421 / 1444

Related Subject Headings

  • Strategic, Defence & Security Studies
  • 4105 Pollution and contamination
  • 4104 Environmental management
  • 0602 Ecology
  • 0502 Environmental Science and Management
  • 0501 Ecological Applications