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ACE inhibitors in hypertension: a US perspective.

Publication ,  Journal Article
Dzau, VJ
Published in: Cardiology
1989

The failure of recent antihypertensive trials to document clearly a reduction in the risk of coronary heart disease (nonfatal or fatal myocardial infarction and sudden death) has important clinical implications. Although the causes of this phenomenon are unknown, it is possible that lipid and metabolic side effects of the antihypertensive drugs used in these studies negated the beneficial effects of blood pressure reduction. Angiotensin-converting enzyme (ACE) inhibitors are lipid neutral and associated with few metabolic side effects, and may be considered over agents that cause adverse effects on such parameters as serum cholesterol, glucose, potassium, and uric acid levels. ACE inhibitors are now emerging in the United States as important first-line therapy for the treatment of hypertension.

Duke Scholars

Published In

Cardiology

DOI

ISSN

0008-6312

Publication Date

1989

Volume

76 Suppl 2

Start / End Page

23 / 30

Location

Switzerland

Related Subject Headings

  • United States
  • Risk Factors
  • Hypertension
  • Humans
  • Coronary Disease
  • Clinical Trials as Topic
  • Cardiovascular System & Hematology
  • Angiotensin-Converting Enzyme Inhibitors
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
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Dzau, V. J. (1989). ACE inhibitors in hypertension: a US perspective. Cardiology, 76 Suppl 2, 23–30. https://doi.org/10.1159/000174556
Dzau, V. J. “ACE inhibitors in hypertension: a US perspective.Cardiology 76 Suppl 2 (1989): 23–30. https://doi.org/10.1159/000174556.
Dzau VJ. ACE inhibitors in hypertension: a US perspective. Cardiology. 1989;76 Suppl 2:23–30.
Dzau, V. J. “ACE inhibitors in hypertension: a US perspective.Cardiology, vol. 76 Suppl 2, 1989, pp. 23–30. Pubmed, doi:10.1159/000174556.
Dzau VJ. ACE inhibitors in hypertension: a US perspective. Cardiology. 1989;76 Suppl 2:23–30.
Journal cover image

Published In

Cardiology

DOI

ISSN

0008-6312

Publication Date

1989

Volume

76 Suppl 2

Start / End Page

23 / 30

Location

Switzerland

Related Subject Headings

  • United States
  • Risk Factors
  • Hypertension
  • Humans
  • Coronary Disease
  • Clinical Trials as Topic
  • Cardiovascular System & Hematology
  • Angiotensin-Converting Enzyme Inhibitors
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology