Baseline hippocampal theta oscillation speeds correlate with rate of operant task acquisition.

Published

Journal Article

Many lines of evidence indicate that theta rhythm, a prominent neural oscillatory mode found in the mammalian hippocampus, plays a key role in the acquisition, processing, and retrieval of memories. However, a predictive neurophysiological feature of the baseline theta rhythm that correlates with the learning rate across different animals has yet to be identified. Here we show that the mean theta rhythm speed observed during baseline periods of immobility has a strong positive correlation with the rate at which rats learn an operant task. This relationship is observed across rats, during both quiet waking (r=0.82; p<0.01) and paradoxical sleep (r=0.83; p<0.01), suggesting that the basal theta frequency relates to basic neurological processes that are important in the acquisition of operant behavior.

Full Text

Duke Authors

Cited Authors

  • Santos, LM; Dzirasa, K; Kubo, R; Silva, MTA; Ribeiro, S; Sameshima, K; Valle, AC; Timo-Iaria, C

Published Date

  • June 2008

Published In

Volume / Issue

  • 190 / 1

Start / End Page

  • 152 - 155

PubMed ID

  • 18378012

Pubmed Central ID

  • 18378012

Electronic International Standard Serial Number (EISSN)

  • 1872-7549

International Standard Serial Number (ISSN)

  • 0166-4328

Digital Object Identifier (DOI)

  • 10.1016/j.bbr.2008.02.032

Language

  • eng