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SPECT-CT compared with conventional imaging modalities for the assessment of the varus and valgus malaligned hindfoot.

Publication ,  Journal Article
Knupp, M; Pagenstert, GI; Barg, A; Bolliger, L; Easley, ME; Hintermann, B
Published in: J Orthop Res
November 2009

The combined single-photon emission computed tomography and conventional computed tomography (SPECT/CT) technique has increased the sensitivity and specificity of bone scans. We examined the value of using SPECT/CT for the assessment of coronal plane hindfoot deformities. Twenty-seven patients with varus (11 patients) or valgus (16 patients) malalignment of the hindfoot were assessed using radiography, conventional CT, bone scintigraphy, and SPECT/CT. The amount of deformity, stage of osteoarthritis, and level of activation on bone scans and SPECT/CT were measured. Activation was assessed in 12 regions of interest. The stage of osteoarthritis seen on plain radiographs correlated significantly with the level of activation detected on bone scans (p < 0.05). No correlation was observed between the amount of deformation and activity, and between bone scan activation and signs of osteoarthritis on CT scans. The varus malaligned ankles showed higher radioisotope uptake in the medial areas, while the valgus malaligned ankles showed increased uptake in the lateral areas (p < 0.05). SPECT/CT may be a valuable tool for the assessment and staging of osteoarthritis. Our findings underline the adverse effects of coronal plane deformity of the hindfoot. In addition, results from this study provide useful information for future basic research on coronal plane deformity of the hindfoot and for determining appropriate surgical approaches.

Duke Scholars

Published In

J Orthop Res

DOI

EISSN

1554-527X

Publication Date

November 2009

Volume

27

Issue

11

Start / End Page

1461 / 1466

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Tomography, Emission-Computed, Single-Photon
  • Sensitivity and Specificity
  • Orthopedics
  • Middle Aged
  • Male
  • Humans
  • Foot Deformities
  • Female
  • Ankle Joint
 

Citation

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Knupp, M., Pagenstert, G. I., Barg, A., Bolliger, L., Easley, M. E., & Hintermann, B. (2009). SPECT-CT compared with conventional imaging modalities for the assessment of the varus and valgus malaligned hindfoot. J Orthop Res, 27(11), 1461–1466. https://doi.org/10.1002/jor.20922
Knupp, Markus, Geert I. Pagenstert, Alexej Barg, Lilianna Bolliger, Mark E. Easley, and Beat Hintermann. “SPECT-CT compared with conventional imaging modalities for the assessment of the varus and valgus malaligned hindfoot.J Orthop Res 27, no. 11 (November 2009): 1461–66. https://doi.org/10.1002/jor.20922.
Knupp M, Pagenstert GI, Barg A, Bolliger L, Easley ME, Hintermann B. SPECT-CT compared with conventional imaging modalities for the assessment of the varus and valgus malaligned hindfoot. J Orthop Res. 2009 Nov;27(11):1461–6.
Knupp, Markus, et al. “SPECT-CT compared with conventional imaging modalities for the assessment of the varus and valgus malaligned hindfoot.J Orthop Res, vol. 27, no. 11, Nov. 2009, pp. 1461–66. Pubmed, doi:10.1002/jor.20922.
Knupp M, Pagenstert GI, Barg A, Bolliger L, Easley ME, Hintermann B. SPECT-CT compared with conventional imaging modalities for the assessment of the varus and valgus malaligned hindfoot. J Orthop Res. 2009 Nov;27(11):1461–1466.
Journal cover image

Published In

J Orthop Res

DOI

EISSN

1554-527X

Publication Date

November 2009

Volume

27

Issue

11

Start / End Page

1461 / 1466

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Tomography, Emission-Computed, Single-Photon
  • Sensitivity and Specificity
  • Orthopedics
  • Middle Aged
  • Male
  • Humans
  • Foot Deformities
  • Female
  • Ankle Joint