Hyperperfusion on perfusion computed tomography following revascularization for acute stroke.
Journal Article (Journal Article)
PURPOSE: To describe the findings of hyperperfusion on perfusion computed tomography (CT) in four patients following revascularization for acute stroke. MATERIAL AND METHODS: In 2002-2003, among a series of 6 patients presenting with an acute stroke and treated with intra-arterial thrombolysis, we observed the presence of hyperperfusion in 3 patients on the follow-up CT perfusion. We included an additional patient who was treated with intravenous thrombolysis and who had hyperperfusion on the follow-up CT perfusion. We retrospectively analyzed their CT perfusion maps. Cerebral blood volume (CBV) and cerebral blood flow (CBF) maps were compared between the affected territory and the normal contralateral hemisphere. RESULTS: In the four patients, the mean CBV and CBF were 3.6 +/- 2.0 ml/100 g and 39 +/- 25 ml/100 g/min in the affected territory compared to the normal side (mean CBV = 2.7 +/- 2.1 ml/100 g, mean CBF = 27 +/- 23 ml/100 g/min). There was no intracranial hemorrhage in the hyperperfused territories. At follow-up CT, some hyperperfused brain areas progressed to infarction, while others retained normal white to gray matter differentiation. CONCLUSION: CT perfusion can demonstrate hyperperfusion, which can be seen in an ischemic brain territory following recanalization.
Full Text
Duke Authors
Cited Authors
- Nguyen, TB; Lum, C; Eastwood, JD; Stys, PK; Hogan, M; Goyal, M
Published Date
- October 2005
Published In
Volume / Issue
- 46 / 6
Start / End Page
- 610 - 615
PubMed ID
- 16334842
International Standard Serial Number (ISSN)
- 0284-1851
Digital Object Identifier (DOI)
- 10.1080/02841850510021607
Language
- eng
Conference Location
- England