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User-defined vascular input function curves: influence on mean perfusion parameter values and signal-to-noise ratio.

Publication ,  Journal Article
Kealey, SM; Loving, VA; Delong, DM; Eastwood, JD
Published in: Radiology
May 2004

The authors reviewed 40 computed tomographic (CT) perfusion studies to determine the effect of arterial and venous input function properties on perfusion parameter values and tissue signal-to-noise ratio (SNR). A 10-subject subset was analyzed to evaluate the effect of varying venous region of interest (ROI) locations. Venous peak enhancement correlated significantly with mean tissue cerebral blood flow (CBF) and cerebral blood volume (CBV); venous and arterial peak enhancement correlated significantly with SNR of perfusion maps. Different ROI locations within the same vein resulted in significantly different CBV and CBF values. Perfusion map parameters are related to peak enhancement within user-selected ROIs. Optimal ROI selection should limit variability and increase quality of CT perfusion images.

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Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

May 2004

Volume

231

Issue

2

Start / End Page

587 / 593

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Humans
  • Female
  • Cerebrovascular Circulation
  • Cerebral Arteries
  • Aged, 80 and over
  • Aged
 

Citation

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Kealey, S. M., Loving, V. A., Delong, D. M., & Eastwood, J. D. (2004). User-defined vascular input function curves: influence on mean perfusion parameter values and signal-to-noise ratio. Radiology, 231(2), 587–593. https://doi.org/10.1148/radiol.2312030489
Kealey, Susan M., Vilert A. Loving, David M. Delong, and James D. Eastwood. “User-defined vascular input function curves: influence on mean perfusion parameter values and signal-to-noise ratio.Radiology 231, no. 2 (May 2004): 587–93. https://doi.org/10.1148/radiol.2312030489.
Kealey SM, Loving VA, Delong DM, Eastwood JD. User-defined vascular input function curves: influence on mean perfusion parameter values and signal-to-noise ratio. Radiology. 2004 May;231(2):587–93.
Kealey, Susan M., et al. “User-defined vascular input function curves: influence on mean perfusion parameter values and signal-to-noise ratio.Radiology, vol. 231, no. 2, May 2004, pp. 587–93. Pubmed, doi:10.1148/radiol.2312030489.
Kealey SM, Loving VA, Delong DM, Eastwood JD. User-defined vascular input function curves: influence on mean perfusion parameter values and signal-to-noise ratio. Radiology. 2004 May;231(2):587–593.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

May 2004

Volume

231

Issue

2

Start / End Page

587 / 593

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Humans
  • Female
  • Cerebrovascular Circulation
  • Cerebral Arteries
  • Aged, 80 and over
  • Aged