Thermal vapor bubble and pressure dynamics during infrared laser ablation of tissue

Journal Article

Free-electron laser irradiation can superheat tissue water, driving thermal vapor bubbles confined by tissue matrix and leading to mechanical tissue failure (ablation). Acoustic transients propagating from an ablation cavity were recorded with a polarization quadrature, interferometric vibrometer. For 3.0 μm infrared irradiation, the shocklike transients with peak pressures in the megapascal range indicate amplification due to bubble collapse. In contrast, for 6.45 μm irradiation, elastic transients with peak pressures in the 0.1 MPa range indicate tissue failure during bubble growth. © 2009 American Institute of Physics.

Full Text

Duke Authors

Cited Authors

  • Wagner, W; Sokolow, A; Pearlstein, R; Edwards, G

Published Date

  • 2009

Published In

Volume / Issue

  • 94 / 1

International Standard Serial Number (ISSN)

  • 0003-6951

Digital Object Identifier (DOI)

  • 10.1063/1.3063127