The Duke FEL Laboratory is a national and international users facility. We describe the current light source capabilities in the infrared, visible, ultraviolet, and Gamma rays. Plans are summarized for the development of two novel beamlines, one for UV-resonant Raman spectroscopy and the other an essentially jitter-free UV-pump, IR-probe 'two-color' source with rapid-scan FTIR time-resolved detection of the broadband infrared. Current applications research is summarized, with a more detailed description of research in corneal would healing.