Directionality and processivity of molecular motors.
Journal Article (Journal Article;Review)
Analysis of a mutant with altered directionality has led to new insights into motor directionality. The prediction from current models for processivity of a two-heads-bound state has been confirmed by electron microscopy for myosin V and by unbinding experiments for kinesin. Evidence is emerging that non-processive motors bind their filament with one head, hydrolyze ATP and then release, requiring binding by a second motor to complete a step.
- Higuchi, H; Endow, SA
- February 2002
Volume / Issue
- 14 / 1
Start / End Page
- 50 - 57
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)