Determinants of motor polarity in the kinesin proteins

Journal Article

Many of the proteins that are members of the kinesin family of microtubule motor proteins are plus-end motors; however, a few of the kinesin proteins have now been found to be minus-end microtubule motors. Overall structural features of the proteins can be used to identify further kinesins that are likely to be minus-end motors. Structural or biochemical differences that may serve as the basis of the 'reversed' polarity of a unique subset of the kinesin proteins are discussed.

Duke Authors

Cited Authors

  • Endow, SA; Cole, D; Cooke, R; Titus, M; Pollack, G

Published Date

  • January 1, 1995

Published In

Volume / Issue

  • 68 / 4 SUPPL.

International Standard Serial Number (ISSN)

  • 0006-3495

Citation Source

  • Scopus