Meiosis, mitosis and microtubule motors.

Journal Article (Journal Article;Review)

A framework for understanding the complex movements of mitosis and meiosis has been provided by the recent discovery of microtubule motor proteins, required for the proper distribution of chromosomes or the structural integrity of the mitotic or meiotic spindle. Although overall features of mitosis and meiosis are often assumed to be similar in mechanism, it is now clear that they differ in several important aspects. These include spindle structure and assembly, and timing of chromosome segregation to opposite poles. Here we review progress in the functional characterization of several newly identified microtubule motor proteins, emphasizing their possible roles in spindle structure and function.

Full Text

Duke Authors

Cited Authors

  • Sawin, KE; Endow, SA

Published Date

  • June 1993

Published In

Volume / Issue

  • 15 / 6

Start / End Page

  • 399 - 407

PubMed ID

  • 8357342

International Standard Serial Number (ISSN)

  • 0265-9247

Digital Object Identifier (DOI)

  • 10.1002/bies.950150606


  • eng

Conference Location

  • United States