Intended single-modality management of T1 and T2 tonsillar carcinomas: retrospective comparison of radical tonsillectomy vs radiation from a single institution.

Journal Article (Journal Article)

BACKGROUND: T1 and T2 tonsillar squamous cell cancer with limited neck disease can be managed with single-modality radiation or surgery. Over 11 years, 17 patients underwent radical tonsillectomies; and 33 patients underwent radiation-based treatments for T1 and T2 and N0 to N2a tonsil cancer. Patients were intended to receive single-modality treatment based on presentation; however, some ultimately received adjuvant treatments. METHODS: A retrospective chart review to compare overall survival (OS), disease-specific survival (DSS), and locoregional control (LRC) between the groups was used. RESULTS: In surgical group, of 17 patients, 11 underwent surgery alone, 3 underwent surgery and radiation, and 3 underwent surgery with concurrent chemoradiation. Five-year OS for the surgical and radiation groups was 93% and 72%, respectively (no significance achieved). Five-year DSS rates (93% and 80%) and LRC (69% and 89%) similarly did not yield any significant difference. CONCLUSION: Surgery remains a viable option in the management of T1 and T2 tonsillar cancers with comparable LRC, OS, and DSS.

Full Text

Duke Authors

Cited Authors

  • Lamarre, ED; Seth, R; Lorenz, RR; Esclamado, R; Adelstein, DJ; Rodriguez, CP; Saxton, J; Scharpf, J

Published Date

  • January 2012

Published In

Volume / Issue

  • 33 / 1

Start / End Page

  • 98 - 103

PubMed ID

  • 21696857

Electronic International Standard Serial Number (EISSN)

  • 1532-818X

Digital Object Identifier (DOI)

  • 10.1016/j.amjoto.2011.02.005


  • eng

Conference Location

  • United States