Analysis of recurrence and survival after hypopharyngeal ablative surgery with radial forearm free flap reconstruction.

Journal Article (Journal Article)

OBJECTIVES/HYPOTHESIS: To address the controversial acceptable distal resection margin for the surgical management of patients with hypopharyngeal cancer. STUDY DESIGN: Retrospective review of the records of 28 consecutive patients who underwent pharyngoesophagectomy and reconstruction with radial forearm free flaps between 1996 to 2001. METHODS: The Kaplan-Meier method was used to estimate survival and recurrence-free time. RESULTS: The minimum follow-up time was 2 years, and there were 14 (50%) patients who had recurrences. Analysis revealed that only one (3%) patient experienced a recurrence at the inferior resection margin, the junction of the free flap reconstruction, and the cervical esophagus. Estimated 4 year survival was 48.5%. CONCLUSIONS: Total laryngopharyngectomy and partial esophagectomy with radial forearm free flap reconstructions in appropriately selected patients with hypopharyngeal cancer does not compromise local recurrence rates at the distal esophageal margin.

Full Text

Duke Authors

Cited Authors

  • Scharpf, J; Esclamado, RM

Published Date

  • March 2005

Published In

Volume / Issue

  • 115 / 3

Start / End Page

  • 429 - 432

PubMed ID

  • 15744151

International Standard Serial Number (ISSN)

  • 0023-852X

Digital Object Identifier (DOI)

  • 10.1097/


  • eng

Conference Location

  • United States