The pathogenesis of vascular thrombosis and its impact in microvascular surgery.

Journal Article (Journal Article)

As the use of free tissue transfer becomes more wide-spread, it is important for both the ablative surgeon and the reconstructive surgeon to understand the factors that contribute to successful revascularized tissue transfer. The purpose of this two part review is to provide a basic science overview of the problem of failed free tissue transfers. The first part will focus on the pathogenesis of thrombosis at the anastomotic site, and part two will discuss the pathogenesis of the no-reflow phenomenon. The pathophysiology and therapeutic interventions to prevent and treat anastomotic thrombosis and the no-reflow phenomenon will be discussed.

Full Text

Duke Authors

Cited Authors

  • Esclamado, RM; Carroll, WR

Published Date

  • July 1999

Published In

Volume / Issue

  • 21 / 4

Start / End Page

  • 355 - 362

PubMed ID

  • 10376756

International Standard Serial Number (ISSN)

  • 1043-3074

Digital Object Identifier (DOI)

  • 10.1002/(sici)1097-0347(199907)21:4<355::aid-hed10>;2-y


  • eng

Conference Location

  • United States