Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development.
Publication
, Journal Article
Betts, MR; Gray, CM; Cox, JH; Ferrari, G
Published in: Expert Rev Vaccines
August 2006
The definition of immune correlates of protection in HIV-1 infection is pivotal to the design of successful vaccine candidates and strategies. Although significant methodological and conceptual strides have been made in our understanding of HIV-specific cellular immunity, we have not yet defined those parameters that have a role in controlling the spread of HIV infection. This review discusses the basis of our understanding of HIV-specific cellular immunity and identifies its shortcomings. Furthermore, potential protective characteristics will be proposed that may ultimately be required for an effective vaccine designed to stimulate cellular immunity against HIV-1.
Duke Scholars
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Published In
Expert Rev Vaccines
DOI
EISSN
1744-8395
Publication Date
August 2006
Volume
5
Issue
4
Start / End Page
505 / 516
Location
England
Related Subject Headings
- Virology
- T-Lymphocytes
- HIV-1
- HIV Infections
- Disease Progression
- CD4-Positive T-Lymphocytes
- Antibody Formation
- Acquired Immunodeficiency Syndrome
- AIDS Vaccines
- 3204 Immunology
Citation
APA
Chicago
ICMJE
MLA
NLM
Betts, M. R., Gray, C. M., Cox, J. H., & Ferrari, G. (2006). Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development. Expert Rev Vaccines, 5(4), 505–516. https://doi.org/10.1586/14760584.5.4.505
Betts, Michael R., Clive M. Gray, Josephine H. Cox, and Guido Ferrari. “Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development.” Expert Rev Vaccines 5, no. 4 (August 2006): 505–16. https://doi.org/10.1586/14760584.5.4.505.
Betts MR, Gray CM, Cox JH, Ferrari G. Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development. Expert Rev Vaccines. 2006 Aug;5(4):505–16.
Betts, Michael R., et al. “Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development.” Expert Rev Vaccines, vol. 5, no. 4, Aug. 2006, pp. 505–16. Pubmed, doi:10.1586/14760584.5.4.505.
Betts MR, Gray CM, Cox JH, Ferrari G. Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development. Expert Rev Vaccines. 2006 Aug;5(4):505–516.
Published In
Expert Rev Vaccines
DOI
EISSN
1744-8395
Publication Date
August 2006
Volume
5
Issue
4
Start / End Page
505 / 516
Location
England
Related Subject Headings
- Virology
- T-Lymphocytes
- HIV-1
- HIV Infections
- Disease Progression
- CD4-Positive T-Lymphocytes
- Antibody Formation
- Acquired Immunodeficiency Syndrome
- AIDS Vaccines
- 3204 Immunology