Association of education with incidence of cognitive impairment in three established populations for epidemiologic studies of the elderly.


Journal Article

We analyzed the association of education, occupation, and sex with incidence of cognitive impairment using data from three communities in the Established Populations for Epidemiologic Studies of the Elderly (EPESE) projects (New Haven, East Boston, and Iowa). Participants were initially interviewed in 1981-1983, with follow-up 3 and 6 years later. Incident cognitive impairment was defined on the basis of either: (1) increase in the number of errors in Short Portable Mental Status Questionnaire (SPMSQ) (i.e. from a baseline level below the cutoff value to a score above the cutoff), or (2) inability to respond to interview questions at a follow-up contact (requiring a proxy informant), or (3) death with a recorded diagnosis of a dementing illness. In multiple logistic regression models, the major factors predicting the development of cognitive impairment were advanced age, any errors on baseline SPMSQ, 8 or fewer years of education, and occupation. Education and occupation remained significant predictors after controlling for age, site, sex, stroke, and baseline SPMSQ score.

Full Text

Duke Authors

Cited Authors

  • White, L; Katzman, R; Losonczy, K; Salive, M; Wallace, R; Berkman, L; Taylor, J; Fillenbaum, G; Havlik, R

Published Date

  • April 1, 1994

Published In

Volume / Issue

  • 47 / 4

Start / End Page

  • 363 - 374

PubMed ID

  • 7730861

Pubmed Central ID

  • 7730861

International Standard Serial Number (ISSN)

  • 0895-4356

Digital Object Identifier (DOI)

  • 10.1016/0895-4356(94)90157-0


  • eng

Conference Location

  • United States